WEB-based GEne SeT AnaLysis Toolkit
 
Translating gene lists into biological insights...
 


User data and parameters: User data: textAreaUpload.txt, Organism: hsapiens, Id Type: ensembl_gene_stable_id, Ref Set: entrezgene, Significance Level: Top10, Statistics Test: Hypergeometric, MTC: BH, Minimum: 2

This table lists the enriched KEGG pathways, number of Entrez IDs in your user data set for the pathway, the corresponding Entrez IDs, and the statistics for the enriched pathway.
The statistic column lists:
Finally, the pathway name is linked to KEGG where the user ids are highlighted, the number of user gene ids is linked to a table with information about the user ids, and the Entrez IDs are linked to Entrez Gene.

PathwayName #Gene EntrezGene Statistics
Cell cycle 12 8318 5347 991 9232 10926 699 990 9088 891 9133 983 1029 C=124;O=12;E=0.21;R=57.17;rawP=2.93e-18;adjP=2.64e-17
Oocyte meiosis 8 5347 699 9088 891 9133 983 991 9232 C=112;O=8;E=0.19;R=42.20;rawP=1.87e-11;adjP=8.41e-11
Progesterone-mediated oocyte maturation 6 5347 699 9088 891 9133 983 C=86;O=6;E=0.15;R=41.22;rawP=8.05e-09;adjP=2.42e-08
p53 signaling pathway 5 6241 891 9133 983 1029 C=68;O=5;E=0.12;R=43.44;rawP=1.16e-07;adjP=2.61e-07
Pyrimidine metabolism 3 7298 6241 7083 C=99;O=3;E=0.17;R=17.90;rawP=0.0006;adjP=0.0011
Pancreatic cancer 2 5888 1029 C=70;O=2;E=0.12;R=16.88;rawP=0.0063;adjP=0.0095
Pathways in cancer 3 5888 332 1029 C=326;O=3;E=0.55;R=5.44;rawP=0.0180;adjP=0.0231
Ubiquitin mediated proteolysis 2 11065 991 C=135;O=2;E=0.23;R=8.75;rawP=0.0221;adjP=0.0249
Metabolic pathways 4 7298 6241 7083 6487 C=1130;O=4;E=1.91;R=2.09;rawP=0.1248;adjP=0.1248


WebGestalt is currently developed and maintained by Jing Wang and Bing Zhang at the Zhang Lab. Other people who have made significant contribution to the project include Dexter Duncan, Stefan Kirov, Zhiao Shi, and Jay Snoddy.

Funding credits: NIH/NIAAA (U01 AA016662, U01 AA013512); NIH/NIDA (P01 DA015027); NIH/NIMH (P50 MH078028, P50 MH096972); NIH/NCI (U24 CA159988); NIH/NIGMS (R01 GM088822).